This is a good question and perhaps a little more complicated than you might guess. The short answer is "yes," with zero-centered diff utilities you can compare segments to see if their utilities are significantly different or not. The quick and (only slightly) dirty way to do this is to just treat the utilities as you would any other measure and run a statistical significance test on them.
Use a t-test if you compare two groups and an analysis of variance if you test more than two; moreover, as you are likely testing the significance of multiple attribute levels you may want to use a multiple comparisons test that corrects for the "false discovery" that can occur when you apply the 5% error rate for one test (i.e. 95% confidence) to multiple tests. For this false discovery correction I like the Benjamini-Hochberg procedure, a nice description of which you can find on Wikipedia.
I mentioned above that this kind of traditional stat test is a good way to test but if you want to be really rigorous you could go into the "draws" files and run a proper Bayesian statistical test. This is a bit more work, however and I suspect your needs will be very nicely met with the traditional stat test.
Either way, if you run these tests and find significant differences you can conclude that your segments have differing preferences. Concluding that they have the SAME preferences is not the flip side of this, of course, as the size of differences you are able to detect is dependent on your sample size.